IMPORTANT NOTICE: At Fortis Healthcare, we are fully supportive of the National priorities set out by the Hon’ble Prime Minister of India. Further to the directives of the Government provided in their press release dated 8th Nov 2016, payments at Government hospitals can be made through 500 and 1000 Rupee denomination notes. In view of the hardship being caused to the large number of patients at private hospitals, we have made an urgent representation to the Government that this exemption should apply equally, for payments, at private hospitals. We are following up with the authorities and hope the Government will step in quickly to resolve this anomaly. Meanwhile, at Fortis hospitals across the country, we continue to accept payments through credit card, debit card and electronic banking transfers. As 500 and 1000 Rupee denomination notes are no longer legal tender we are only accepting 100 Rs and lower currency notes. As per Government regulation, a PAN card and legitimate ID proof is however required for payments in cash exceeding Rs 50,000. Meanwhile we continue to ensure that emergency cases get immediate medical attention without delay whatsoever and have put in more administrative staff and help desks to assist patients.

Castleman disease

Castleman disease is a rare disorder that involves an overgrowth (proliferation) of cells in your body's disease-fighting network (lymphatic system). Also known as giant lymph node hyperplasia and angiofollicular lymph node hyperplasia, Castleman disease can occur in a localized (unicentric) or widespread (multicentric) form.

Treatment and outlook vary, depending on the type of Castleman disease you have. The localized type can usually be successfully treated with surgery.

Sometimes associated with HIV infection, multicentric Castleman disease can be life-threatening. Multicentric Castleman disease is also associated with other cell-proliferation disorders, including cancer of the lymphatic system (lymphoma), Kaposi's sarcoma and POEMS syndrome.


Symptoms Causes Risk factors Complications

There are two basic types of Castleman disease:

  • Unicentric Castleman disease. This localized form of the disease affects only a single gland (lymph node) in your lymphatic system.
  • Multicentric Castleman disease. This type affects multiple lymph nodes and lymphatic tissues, and can severely weaken your immune system.

Multicentric Castleman disease can be further classified as:

  • Multicentric Castleman disease without POEMS syndrome
  • Multicentric Castleman disease with POEMS syndrome that involves areas of abnormal bone (osteosclerotic lesions)
  • Multicentric Castleman disease with POEMS syndrome without osteosclerotic lesions

Unicentric Castleman disease

Many people with unicentric Castleman disease don't notice any signs or symptoms. The diseased lymph node is usually located in the chest, neck or abdomen. When signs and symptoms are present, they may include:

  • A feeling of fullness or pressure in the chest or abdomen that can cause difficulty breathing or eating
  • An enlarged lump under the skin in the neck, groin or armpit
  • Unintended weight loss
  • Less commonly, fever, night sweats and weakness

Multicentric Castleman disease

Most people with multicentric Castleman disease experience:

  • Fever
  • Night sweats
  • Fatigue and weakness
  • Loss of appetite
  • Unintended weight loss
  • Enlarged lymph nodes, usually around the neck, collarbone, underarm and groin areas
  • Enlarged liver or spleen

Other, less common symptoms include:

  • Nerve damage in the hands and feet that leads to numbness (peripheral neuropathy)
  • Skin rash

When to see a doctor

If you notice an enlarged lymph node on the side of your neck or in your underarm, collarbone or groin area, talk to your doctor. Also call your doctor if you experience a persistent feeling of fullness in your chest or abdomen, fever, fatigue, or unexplained weight loss.


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