Nephrotic syndrome

Nephrotic syndrome is a kidney disorder that causes your body to excrete too much protein in your urine.

Nephrotic syndrome is usually caused by damage to the clusters of small blood vessels in your kidneys that filter waste and excess water from your blood. Nephrotic syndrome causes swelling (edema), particularly in your feet and ankles, and increases the risk of other health problems.

Treatment for nephrotic syndrome includes treating the underlying condition that's causing it and taking medications. Nephrotic syndrome can increase your risk of infections and blood clots. Your doctor may recommend medications and dietary changes to prevent these and other complications of nephrotic syndrome.

Symptoms Causes Risk factors Complications

Signs and symptoms of nephrotic syndrome include:

  • Severe swelling (edema), particularly around your eyes and in your ankles and feet
  • Foamy urine, which may be caused by excess protein in your urine
  • Weight gain due to excess fluid retention

When to see a doctor

Make an appointment with your doctor if you have any signs or symptoms that worry you.

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