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Bone marrow in our bones is responsible for formation of blood cells. In fact, all the blood cells are formed by a subset of bone marrow cells known as “hematopoietic stem cells” or simple “stem cells”. These blood cells have special characteristics i.e. they can renew themselves, and have the capability to develop into any type of blood cells. Nowadays, hematopoietic stem cells can also be obtained from peripheral blood after treatment with certain growth factors or from umbilical cord. Thus, “Hematopoietic stem cell transplantation” is now preferred to “Bone marrow transplantation”, wherein the stem cells from bone marrow that produce red blood cells, white blood cells, and platelets are injected into a recipient after a short course of chemotherapy called conditioning. Today, this is a viable option for several disorders and with a continued research, success has remarkably improved.

Why Choose Us

  • Team of eight doctors including haematologists and haemato-oncologists.
  • Completed over 1200+ bone marrow transplants.
  • 22-bedded transplant unit
  • One of the largest centres for multiple sclerosis, sickle cell and aplastic anaemia treatment
  • Global standard of infection control practises
  • One of the few centres performing matched unrelated donor transplant for thalassemia

Our Team of Experts

  • Dr. Vikas Dua
  • Dr. Sohini Chakraborty
Find us
Fortis Memorial Research institute, Sector-44, Gurugram, Opp. Huda City Centre, Gurugram, Haryana 122002
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  • What is a Bone Marrow Transplant (BMT) ?
    A Bone Marrow Transplant, also known as a Hematopoietic Stem Cell Transplant (HSCT), is a medical procedure that involves replacing damaged or diseased bone marrow with healthy stem cells. These stem cells can come from the patient themselves (autologous transplant) or a compatible donor (allogeneic transplant).
  • What is the purpose of a Bone Marrow Transplant ?
    The primary goal of a Bone Marrow Transplant is to treat various conditions like certain types of cancer (leukemia, lymphoma, multiple myeloma), severe aplastic anemia, and genetic disorders that affect the production of blood cells.
  • How does a Bone Marrow Transplant work?
    The procedure involves three main stages: a. Conditioning: High-dose chemotherapy, radiation, or a combination of both is administered to destroy the diseased marrow and suppress the immune system to prevent rejection. b. Transplantation: Healthy stem cells are infused into the patient's bloodstream, where they migrate to the bone marrow and start producing new blood cells. c. Engraftment: It is the phase where the transplanted stem cells begin to grow and produce healthy blood cells.
  • What types of Bone Marrow Transplants are there?
    There are three main types of Bone Marrow Transplants: a. Autologous Transplant: The patient receives their previously collected and stored stem cells. b. Allogeneic Transplant: Stem cells come from a healthy donor whose tissue type closely matches the patient's. c. Syngeneic Transplant: The stem cells come from an identical twin of the patient.
  • How is a donor matched for an allogeneic transplant?
    Human leukocyte antigen (HLA) testing is performed to determine the compatibility between the patient and potential donors. The more closely the HLA markers match, the better the chance of a successful transplant.
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