Stage 4 prostate cancer

Stage 4 prostate cancer is cancer that begins in the prostate and grows to involve nearby organs or spreads to other areas of the body.

Stage 4 prostate cancer is an uncommon diagnosis. Most cases of prostate cancer are diagnosed at an earlier stage, when the cancer is confined to the prostate.

Treatments may slow or shrink an advanced prostate cancer, but for most men, stage 4 prostate cancer isn't curable. Still, treatments can extend your life and reduce the signs and symptoms of cancer.

Symptoms Causes Risk factors

Signs and symptoms of stage 4 prostate cancer may include:

  • Painful urination
  • Decreased force in the stream of urine
  • Blood in the semen
  • Erectile dysfunction
  • Bone pain
  • Swelling in the legs
  • Fatigue
  • Frequent infections

When to see a doctor

Make an appointment with your doctor if you have any persistent signs or symptoms that worry you.

Doctors aren't certain what causes stage 4 prostate cancer.

Stage 4 prostate cancer occurs when a prostate cancer grows large enough to involve nearby organs, such as the bladder, or when cancer cells break away from the prostate and spread to other areas of the body.

Prostate cancer cells that spread beyond the prostate most often travel to the:

  • Lymph nodes
  • Bones
  • Liver

Factors that may increase your risk of stage 4 prostate cancer include:

  • A family history of prostate cancer. Men with certain inherited gene mutations have an increased risk of more aggressive prostate cancers.
  • African-American race. Black men have an increased risk of aggressive prostate cancer.
© 1998-2015 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Terms of use


Feedback Form