Whipple's disease is a rare bacterial infection that most often affects your gastrointestinal system. Whipple's disease interferes with normal digestion by impairing the breakdown of foods, such as fats and carbohydrates, and hampering your body's ability to absorb nutrients.
Whipple's disease also can infect other organs, including your brain, heart, joints and eyes.
Without proper treatment, Whipple's disease can be serious or fatal. However, a course of antibiotics can treat Whipple's disease.