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Sickle Cell and Pregnancy
Obstetrics and Gynaecology

Sickle Cell and Pregnancy: Considerations for Expectant Mothers

Dr. Mukta Kapila Aug 28, 2023

Pregnancy is a joyous and transformative journey, but for women with sickle cell disease (SCD), it comes with unique challenges and considerations. SCD is a genetic blood disorder characterized by the presence of abnormal hemoglobin, leading to misshapen red blood cells. This blog explores the complexities of pregnancy in women with sickle cell disease, addressing important considerations, potential risks, and strategies for a safe and healthy pregnancy.

 Understanding Sickle Cell Disease and Pregnancy

 Sickle cell disease affects the structure and function of red blood cells, causing them to become rigid and assume a sickle shape. This alteration reduces their ability to transport oxygen, leading to anemia and increased susceptibility to pain crises. Pregnancy can exacerbate these symptoms, as the body demands more blood to support the growing fetus, putting additional strain on the circulatory system.

 Preparation and Planning

1. Pre-Pregnancy Counselling: Women with sickle cell disease should seek pre-pregnancy counseling from healthcare professionals experienced in managing high-risk pregnancies. These consultations help assess the individual's health status, identify potential complications, and optimize overall health before conception. 

2. Genetic Counseling: Genetic counseling is crucial for couples with sickle cell trait or disease. Understanding the genetic risks associated with SCD can assist couples in making informed decisions regarding family planning and prenatal testing.

 3. Medication and Treatment Review: Before attempting to conceive, expectant mothers with SCD should review their current medications and treatment plans with their healthcare team. Some medications may need adjustments to ensure safety during pregnancy.

Prenatal Care and Monitoring

1. Frequent Check-ups: Regular prenatal check-ups are essential for women with SCD to closely monitor their health and the baby's development. These visits allow healthcare providers to detect and address any issues promptly.

 2. Blood Transfusions: In some cases, pregnant women with severe SCD complications may require blood transfusions to manage anemia and reduce the risk of complications.

 3. Fetal Monitoring: Fetal monitoring during pregnancy helps ensure the baby's well-being and can alert healthcare providers to any signs of distress.

 4. Monitoring for Preeclampsia: Women with SCD have an increased risk of preeclampsia, a condition characterized by high blood pressure and organ damage during pregnancy. Early detection and management are vital to safeguard both mother and baby.

Managing Pain and Crises

 1. Pain Crisis Management: Pregnant women with SCD are at higher risk of pain crises due to increased blood volume and stress on the body. Adequate pain management is essential to minimize discomfort and maintain the well-being of both mother and baby.

 2. Hydration: Staying well-hydrated is crucial for pregnant women with SCD, as dehydration can trigger pain crises. Adequate fluid intake helps reduce the risk of complications.

 Delivery and Postpartum Care

 1. Delivery Planning: The mode of delivery for women with SCD depends on individual health status, the baby's condition, and the presence of any complications. Vaginal delivery may be preferred in many cases, but cesarean section may be necessary in certain situations.

 2. Postpartum Care: Postpartum care is critical for women with SCD, as they are at increased risk of complications during the postpartum period. Close monitoring, pain management, and support are essential for a smooth recovery.

 Potential Risks and Complications

 1. Anemia: Pregnant women with SCD are prone to developing more severe anemia, necessitating close monitoring and appropriate interventions.

 2. Preterm Birth: SCD increases the risk of preterm birth, which can lead to complications for the baby, such as respiratory distress syndrome.

 3. Infections: SCD can weaken the immune system, making expectant mothers more susceptible to infections. Vaccinations and preventive measures are vital during pregnancy.

 4. Organ Damage: Pregnancy places additional strain on the circulatory system, potentially leading to organ damage in women with SCD. 

 

 

Sickle Cell and Pregnancy Pregnancy SickleCellAwareness Pregnancy Complications SickleCellTrait SickleCellDisease AnaemiaInPregnancy SickleCellTreatment HealthyPregnancy NewbornScreening

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Dr. Mukta Kapila
DIRECTOR & UNIT HEAD -OBSTETRICS & GYNAECOLOGY | Fortis Gurgaon
  • Obstetrics and Gynaecology | Obstetrics and Gynaecology
  • Date 30 Years
  • INR 1500

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