Peritoneal Dialysis Procedure: Purpose, Risks, Treatment and Results | Fortis Healthcare

Peritoneal dialysis

Peritoneal dialysis (per-ih-tuh-NEE-ul di-AL-uh-sis) is a way to remove waste products from your blood when your kidneys can no longer do the job adequately. During peritoneal dialysis, blood vessels in your abdominal lining (peritoneum) fill in for your kidneys, with the help of a fluid (dialysate) that flows into and out of the peritoneal space.

Peritoneal dialysis differs from hemodialysis, a more commonly used blood-filtering procedure. With peritoneal dialysis, you can give yourself treatments at home, at work or while traveling. You may be able to use fewer medications and eat a less restrictive diet than you can with hemodialysis.

Peritoneal dialysis isn't an option for everyone with kidney failure. You need manual dexterity and the ability to care for yourself at home or a reliable caregiver.


Why it's done Risks How you prepare What you can expect Results

Peritoneal dialysis may be done to manage kidney failure until a kidney transplant is possible. Kidney failure itself usually results from a long-term (chronic) disease that causes kidney damage over a number of years. Common causes of kidney failure include:

  • Diabetes
  • High blood pressure (hypertension)
  • Kidney inflammation (glomerulonephritis)
  • Multiple cysts in the kidneys (polycystic kidney disease)

Your doctor can help you decide which type of dialysis will work best for you and when you should start, based on several factors:

  • Your overall health
  • Your kidney function (as measured by blood and urine tests)
  • Your personal preferences
  • Your home situation

Peritoneal dialysis may be the better option if:

  • You can't tolerate the rapid changes of fluid balance associated with hemodialysis. During hemodialysis, your blood is pumped into a machine to be filtered and then returned to your body.
  • You want to minimize the disruption of your daily activities and work or travel more easily.

Peritoneal dialysis might not work for you if:

  • You have extensive surgical scars in your abdomen
  • You have a large abdominal hernia
  • You have a limited ability to care for yourself or lack caregiving support at home
  • You have inflammatory bowel disease or frequent bouts of diverticulitis

Most people who require dialysis face a variety of serious health problems, including diseases that cause kidney failure as well as kidney failure itself. Dialysis prolongs life for many people, but life expectancy for those who need the procedure is still lower than that of the general population.

The main complications of peritoneal dialysis are:

  • Infections. The most common problem for people receiving peritoneal dialysis is peritonitis, an infection of the lining of the abdominal cavity (peritoneum). An infection can also develop at the site where the tube (catheter) is inserted to carry the cleansing fluid into and out of your abdomen.
  • Weight gain. The fluid used to clean your blood in peritoneal dialysis contains sugar (dextrose). You may take in several hundred calories each day by absorbing some of this fluid, known as dialysate. Weight gain may follow. The extra calories can also lead to high blood sugar especially if you have diabetes.
  • Weakening of the abdominal muscles (hernia). Holding fluid in your abdomen for long periods may strain your belly muscles.

Before you start peritoneal dialysis, you will receive training on what the procedure involves and how to use the equipment. Plus, you'll need an operation to insert the catheter — the thin, soft plastic tube that carries the dialysis solution in and out of your abdomen. You may receive local or general anesthetics for the surgical insertion procedure. Usually the surgeon places the tube near your bellybutton.

Your doctor will probably recommend waiting at least two weeks before starting treatment so that the catheter site has time to heal.

In peritoneal dialysis, a sterile cleansing solution (dialysate) flows through the catheter into your abdomen. The solution stays in your abdomen for a prescribed period of time, known as dwell time. During this dwell time, waste, chemicals and extra fluid in your blood pass from tiny blood vessels (capillaries) in the lining of your abdominal cavity (peritoneum) into the dialysis solution. The solution contains a sugar that draws wastes and extra fluid through the capillaries in your peritoneum into your abdomen. Your belly may feel fuller than usual while the dialysis solution is there, but it's generally not uncomfortable.

When the dwell time is over, the solution, along with waste products drawn from your blood and any excess fluid, drains into a sterile collection bag. The process of filling and then draining your abdomen is called an exchange.

Different methods of peritoneal dialysis have different schedules of daily exchanges. The two main schedules are continuous ambulatory peritoneal dialysis (CAPD) and continuous cycling peritoneal dialysis (CCPD). Some people use a combination of both methods.

Continuous ambulatory peritoneal dialysis (CAPD)

With this form of peritoneal dialysis, you fill your abdomen with dialysis solution and later drain the fluid. Gravity moves the fluid through the tube and into and out of your belly.

Each exchange includes filling your abdomen with dialysate fluid, letting the fluid dwell in your abdomen, then draining the fluid. You may need three to four exchanges during the day and one with a longer dwell time while you sleep. You can do the exchanges at home, work or any clean place. You're free to go about your normal activities while the dialysis solution dwells in your abdomen between exchanges.

Continuous cycling peritoneal dialysis (CCPD)

With CCPD, which may also be called automated peritoneal dialysis (APD), a machine called an automated cycler performs three to five exchanges at night while you sleep. The cycler automatically fills your abdomen with dialysis solution, allows it to dwell there and then drains it to a sterile drainage bag that you empty in the morning. This gives you more flexibility during the day, but you must remain attached to the machine for 10 to 12 hours at night. In the morning, you begin one exchange with a dwell time that lasts the entire day. You're not connected to the machine during the day.

Which form of peritoneal dialysis is best for you depends on your lifestyle, personal preferences and medical condition. You may also customize your program by combining the two forms. For instance, if you're using CCPD, you may do one extra exchange in the afternoon to remove more waste and prevent absorption of too much fluid.

The efficacy of the peritoneal dialysis procedure is dependent of multiple factors including:

  • The fill volume i.e. the amount of dialysate the patient uses during the dialysis.
  • The size of the patient
  • Length of the dwell time
  • The peritoneal transport rate i.e. the swiftness of the peritoneum to clear the waste from the blood.
  • The number of exchanges performed each day.
  • Sugar (dextrose) concentration present in the dialysate solution.

The doctor also prescribes certain tests to the patient, in first few weeks of the treatment, in order to check the efficacy of the peritoneal dialysis, as mentioned below.

  • Peritoneal equilibrium test (PET) – This test evaluates the amount of dextrose (sugar) absorbed from the bag of the used dialysate fluid. After a 4-hour exchange, this test also helps in evaluating the amount of the waste products, creatinine and urea, still present in the dialysate.
  • Clearance test – Samples of the used dialysate and the venous blood of the patient are collected to compare the amount of urea present in the used dialysis fluid and in the bloodstream. If the patient is able to give a urine sample, then the doctor uses that sample to evaluate the concentration of urea.

If the patient's reports show that the dialysis is not able to remove the required amount of waste from the blood, then the doctor changes the dialysis routine. This may involve the increase in the amount of dialysate used in each exchange, the number of exchanges or using an increased amount of sugar concentration. 

The patient can improve the results of peritoneal dialysis by following certain precautions as mentioned below.

  • Eating a healthy and nutritious diet e.g. phosphorus and low sodium diet.
  • Taking the medicines on time and as prescribed.
  • Try to keep a check on the blood pressure
  • Prevent building up of phosphorus in the blood
  • Medicines to increase the red blood cells and control the amount of some nutrients in the blood.

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